If you’re a fan of spinach and artichoke dip, this chicken casserole is about to become a favorite in your weekly meal rotation. Creamy, cheesy, and loaded with flavor, spinach and artichoke chicken casserole transforms a classic appetizer into a hearty, satisfying dinner. It’s easy to make, great for leftovers, and perfect for feeding a crowd or prepping ahead for busy weeknights.
At its core, this casserole combines tender pieces of chicken breast with a rich, creamy sauce made from cream cheese, sour cream, and grated Parmesan. The addition of mozzarella adds that gooey, melty texture everyone loves. Spinach brings color and nutrients, while marinated artichoke hearts add a slightly tangy contrast that balances the richness of the dish.
What makes this casserole truly convenient is how flexible it is. You can use rotisserie chicken for a time-saving shortcut or bake and shred fresh chicken breasts. Frozen spinach works just as well as fresh (just be sure to drain it thoroughly), and the casserole can be assembled in advance and baked when you’re ready to eat. If you’re feeding a larger group, double the recipe and bake it in a larger dish — it’s always a hit at potlucks and family gatherings.
This dish pairs beautifully with a simple green salad or roasted vegetables. If you want something more indulgent, serve it over pasta or with warm, crusty bread to soak up the sauce. It’s comfort food at its best — familiar, flavorful, and incredibly satisfying.
Spinach and artichoke chicken casserole is a smart way to bring together the creamy dip flavors you love with protein and veggies in one comforting meal. Whether it’s a weeknight dinner or a cozy weekend treat, it’s a recipe worth keeping in your rotation.
Ingredients
- 2 cups cooked chicken breast shredded or cubed
- 1 package frozen spinach thawed and drained
- 1 can artichoke hearts drained and chopped
- 1 cup sour cream
- 1 cup cream cheese softened
- 1 cup mozzarella cheese shredded
- 1 cup parmesan cheese grated
- 1 tsp garlic powder
- 0.5 tsp salt
- 0.5 tsp pepper
Instructions
- Preheat your oven to 375°F (190°C).
- In a large bowl, combine the cooked chicken, spinach, and artichoke hearts.
- In another bowl, mix sour cream, cream cheese, garlic powder, salt, and pepper until smooth.
- Add the cheese mixture to the chicken and spinach mixture and stir to combine.
- Transfer the mixture to a baking dish and top with mozzarella and parmesan cheese.
- Bake for 45 minutes, or until the top is golden brown and bubbly.
Nutrition
Recipe rocks! NEXT LEVEL COMFORT FOOD!!! Highly recommend. 😊
Totally agree! This dish is amazing, my family can’t get enough of it! 🤤
Looks good, but I don’t trust spinach. Is it really that tasty? 🤨
I don’t like spinach much, but this was surprisingly good! Will make again.
Eh, it was alright. I think I prefer my chicken plain, not mixed with all this stuff.
This is sooo good! I made it for a family gathering and everyone loved it!
I donno, looks too cheesy for me. Is it really that good? 🤔
That’s awesome to hear! I love when a recipe is a hit at gatherings. Can’t wait to try this myself!
Too much cheese! I mean, who needs that much mozzarella, right? Not trying this again.
I made this for my family dinner, and they ate it all. Fantastic recipe!
Yummm. I just love casseroles! Gonna try this! 😍
Really easy to make and tastes great! Perfect for busy weeknights. 😋
I made this last night and my family loved it! So creamy and delicious. 😍
Spinach tastes nasty sometimes. No thanks on this one.😝
Easiest dish I’ve made, but my kids didn’t like the artichokes. Not their thing.
Artichokes can be hit or miss with kids! Maybe try spinach only next time? 🤷♀️
This doesn’t look like a real recipe… What’s artichoke anyway?
I used leftover turkey instead of chicken, and it turned out great! Highly recommend!
Spinach and artichoke? Didn’t know those two could work together. But I guess they can!
Doesn’t look like the picture, but it tasted good! Next time I’ll double the artichokes.
Can I use fresh spinach instead of frozen? Just wondering!
I dunno, isn’t frozen easier? Fresh might make it soggy. 🤔
Yes, you can definitely use fresh spinach! Just make sure to wilt it down first so it’s not too watery.
I don’t know, it was kinda bland. I expected more flavor, maybe add some spices or something.
This casserole is amazing! So creamy and delicious. My family loved it!
My kids are picky eaters, but they gobbled this up! Definitely a win for busy weeknights.
Not bad but I prefer my casseroles with more veggies. Too much cheese for my taste!
This casserole was amazing! So creamy and delicious. Everyone loved it!
This was amazing! Super creamy and cheesy, my family devoured it. Definitely a keeper!
Honestly, I was skeptical about spinach and artichoke in a casserole, but it worked! Great recipe.
Doesn’t seem like a healthy option with all that cheese. Not for me.
So easy to make! I added some chopped bell peppers for extra color. Yum!
It turned out a bit bland for me, maybe I should’ve added some spices or hot sauce.
I agree! It definitely needs more flavor. Try adding some cayenne or even a splash of lemon juice next time!
Bland? Nah, I think it’s fine as is. Just don’t expect it to be like taco night every time!
This is the best casserole I have ever tasted! My family loved it. Thank you for sharing!
Could you substitute the chicken for something else? I don’t eat meat. Also, why so much cheese?
Why so much cheese? I mean, cheese is like the best part! But if you don’t want chicken, maybe use more spinach? Sounds good?
You could definitely use tofu or chickpeas instead of chicken! And about the cheese, it helps make it creamy and delicious! But you can always reduce it if you want.
I made this last night, but I think I added too much salt. It was kinda salty!
Too much cheese for my taste. Kind of overwhelmed the other flavors.
Wut kind of cheese is that? There’s too many types! I just used cheddar.
I think mozzarella and parmesan are usually the best for this! Cheddar might change the taste too much. 🤔
I dunno, it was kinda bland. Maybe use more spices? I expected more flavor.
I don’t know about all these ingredients. Can you just use any cheese? Like cheddar?
You can use cheddar, but it won’t taste the same. The original recipe is all about that creamy flavor with mozzarella and parmesan. Just a heads up!