Spinach and Artichoke Chicken Casserole

If you’re a fan of spinach and artichoke dip, this chicken casserole is about to become a favorite in your weekly meal rotation. Creamy, cheesy, and loaded with flavor, spinach and artichoke chicken casserole transforms a classic appetizer into a hearty, satisfying dinner. It’s easy to make, great for leftovers, and perfect for feeding a crowd or prepping ahead for busy weeknights.

At its core, this casserole combines tender pieces of chicken breast with a rich, creamy sauce made from cream cheese, sour cream, and grated Parmesan. The addition of mozzarella adds that gooey, melty texture everyone loves. Spinach brings color and nutrients, while marinated artichoke hearts add a slightly tangy contrast that balances the richness of the dish.

What makes this casserole truly convenient is how flexible it is. You can use rotisserie chicken for a time-saving shortcut or bake and shred fresh chicken breasts. Frozen spinach works just as well as fresh (just be sure to drain it thoroughly), and the casserole can be assembled in advance and baked when you’re ready to eat. If you’re feeding a larger group, double the recipe and bake it in a larger dish — it’s always a hit at potlucks and family gatherings.

This dish pairs beautifully with a simple green salad or roasted vegetables. If you want something more indulgent, serve it over pasta or with warm, crusty bread to soak up the sauce. It’s comfort food at its best — familiar, flavorful, and incredibly satisfying.

Spinach and artichoke chicken casserole is a smart way to bring together the creamy dip flavors you love with protein and veggies in one comforting meal. Whether it’s a weeknight dinner or a cozy weekend treat, it’s a recipe worth keeping in your rotation.

Spinach and Artichoke Chicken Casserole

3.63 from 109 votes

This Spinach and Artichoke Chicken Casserole is a creamy and cheesy dish that’s easy to prepare and packed with flavor. Perfect for a comforting weeknight dinner.

Servings 1 people

Prep Time 15 minutes mins

Cook Time 45 minutes mins

Total Time 1 hour hr

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Ingredients

  

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• 2 cups cooked chicken breast shredded or cubed
• 1 package frozen spinach thawed and drained
• 1 can artichoke hearts drained and chopped
• 1 cup sour cream
• 1 cup cream cheese softened
• 1 cup mozzarella cheese shredded
• 1 cup parmesan cheese grated
• 1 tsp garlic powder
• 0.5 tsp salt
• 0.5 tsp pepper

Instructions

 

• Preheat your oven to 375°F (190°C).
• In a large bowl, combine the cooked chicken, spinach, and artichoke hearts.
• In another bowl, mix sour cream, cream cheese, garlic powder, salt, and pepper until smooth.
• Add the cheese mixture to the chicken and spinach mixture and stir to combine.
• Transfer the mixture to a baking dish and top with mozzarella and parmesan cheese.
• Bake for 45 minutes, or until the top is golden brown and bubbly.

Nutrition

Serving: 1gCalories: 350kcalCarbohydrates: 6gProtein: 30gFat: 22gSaturated Fat: 10gPolyunsaturated Fat: 2gMonounsaturated Fat: 6gCholesterol: 75mgSodium: 720mgPotassium: 240mgFiber: 3gSugar: 2gVitamin A: 1000IUVitamin C: 6mgCalcium: 200mgIron: 2mg

Calories: 350kcal

Meal Type: Dinner

Cuisine: Italian

Keyword: Casserole, dinner, recipe

Cooking Method: Baked

Time: 30-45 Min

Level: Easy

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