Cook the orzo pasta according to package instructions. Drain and set aside.
In a large skillet, heat the olive oil over medium heat. Add the minced garlic and red pepper flakes and sauté for 1-2 minutes.
Add the shrimp to the skillet and cook until pink and opaque, about 3-4 minutes per side. Remove the shrimp from the skillet and set aside.
In the same skillet, add the chopped artichoke hearts and sauté for 3-4 minutes.
Add the cooked orzo pasta to the skillet and toss to combine with the artichoke hearts.
Return the shrimp to the skillet and cook for an additional 1-2 minutes to heat through.
Season with salt and pepper to taste.
Serve the shrimp and artichoke heart orzo hot, garnished with chopped parsley and lemon wedges.